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国家自然科学基金(81000456)

作品数:2 被引量:2H指数:1
相关作者:王海业张书垣刘云飞麻颖宜沈颉飞更多>>
相关机构:四川大学更多>>
发文基金:国家自然科学基金四川省科技支撑计划更多>>
相关领域:医药卫生更多>>

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Corrosion behaviours of the dental magnetic keeper complexes made by different alloys and methods
2016年
The keeper and cast dowel–coping, as a primary component for a magnetic attachment, is easily subjected to corrosion in a wet environment, such as the oral cavity, which contains electrolyte-rich saliva, complex micro?ora and chewing behaviour and so on. The objective of this in vitro study was to examine the corrosion resistance of a dowel and coping-keeper complex fabricated by ?nish keeper and three alloys(cobalt–chromium, Co Cr; silver–palladium–gold, Pd Au; gold–platinum, Au Pt) using a laserwelding process and a casting technique. The surface morphology characteristics and microstructures of the samples were examined by means of metallographic microscope and scanning electron microscope(SEM). Energy-dispersive spectroscopy(EDS) with SEM provided elements analysis information for the test samples after 10% oxalic acid solution etching test. Tafel polarization curve recordings demonstrated parameter values indicating corrosion of the samples when subjected to electrochemical testing. This study has suggested that massive oxides are attached to the surface of the Co Cr–keeper complex but not to the Au Pt–keeper complex. Only the keeper area of cast Co Cr–keeper complex displayed obvious intergranular corrosion and changes in the Fe and Co elements. Both cast and laser-welded Au Pt–keeper complexes had the highest free corrosion potential, followed by the Pd Au–keeper complex. We concluded that although the corrosion resistance of the Co Cr–keeper complex was worst, the keeper surface passive ?lm was actually preserved to its maximum extent. The laser-welded Co Cr–and Pd Au–keeper complexes possessed superior corrosion resistance as compared with their cast specimens, but no signi?cant difference was found between the cast and laser-welded Au Pt–keeper complexes. The Fe-poor and Cr-rich band, appearing on the edge of the keeper when casting, has been proven to be a corrosion-prone area.
Min-Ke WuNing SongFei LiuLiang KouXiao-Wen LuMin WangHang WangJie-Fei Shen
细胞内渗透压改变对三叉神经电压门控钠离子通道电流的影响被引量:2
2012年
目的探讨细胞内液渗透压对三叉神经节神经元(TRGN)上的电压门控钠离子通道(VGSCs)的生物力学影响。方法 TRGN细胞从SD乳鼠分离出来之后,运用膜片钳全细胞记录的方法对VGSCs电流进行记录和分析,通过调节电极内液的组成成分来控制细胞内液渗透压;再与正常渗透压相对比,探讨低渗(260 mOsm)和高渗(350 mOsm)对通道激活和失活动力学的影响。结果与对照组相比较,细胞内液低渗刺激可以影响VGSCs电流的激活和失活特性,包括V0.5、失活曲线(G-V曲线)特征均有明显的统计学意义(P<0.05);然而对于细胞内高渗刺激,仅VGSCs电流的失活特性有一定改变,包括失活速率和k值。结论三叉神经细胞上VGSCs的动力学参数可以通过细胞内液低渗和高渗进行调节,并可表现为不同的特征。
沈颉飞王海业麻颖宜刘云飞张书垣杜莉
关键词:电压门控钠离子通道电生理特性
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