β-Cyclodextrin(β-CD)-containing acrylic monomers were synthesized by using dicyclohexylcarbodiimide(DCC)as catalyst.Synthesis and characterization of using different reaction conditions,and the different mole cular structure with different substitution degree of β-CD-containing acrylic monomers were synthesized.Two kinds of β-CD-containing acrylic monomers,β-CD-3-A and β-CD-6-A carrying the same vinyl,were prepared reying on their reactivity of different hydroxyl groups in β-CD.Nuclear magnetic resonance(13C NMR)data indicated that,for β-CD-3-A,acylation occurs at C-2 and C-3 position of β-CD,and for β-CD-6-A,the acylation occurs at its C-2 and C-6 position,respectively.Moreover,the mono-[6-(2-acryloylaminoethyl)amino]-6-β-CD was obtained using acrylic acid as a raw material under the DCC catalyst.Its structure was confirmed by elemental analysis,1H NMR and IR.
A poly(N-isopropylacrylamide)/β-Cyclodextr in (PNIPAM/β-CD) ionic polymer was synthesized by the reaction of poly( N-isopropylacrylamide-co-acryl acid) (poly(NIPAM-co-AA) with mo no-6-ethanolamine-β-cyclodextrin (EAA-β-CD).EAA-β-CD was synthesized via the reaction of mono-6-OTs-β-CD(Ts= p-toluensulfo nyl) with E.The ionic polymer was characterized by means of FT-IR and UV-V isi ble spectroscopes,and DSC.The result shows that the formation of ionic interacti on between poly(NIPAM-co-) and E-β-CD leads to an increase of t he glass transition temperature (T g) of poly(NIPAM-co-).In additio n,not only the ionic polymer exhibits a well-defined lower critical solution te mperature (LCST),but also β-CD on the polymer backbone can be modulated by changing the pH values,as compared with β-CD-conjugated polymers with co valent bonds.Also,β-CD can easily be bound to the polymer backbone in form of free,or inclusion complex.It is expected that the polymer may find some usef ul applications such as drug delivery system.
