Copper and zinc interaction on clearance from water and distribution in different tissues was investigated for the freshwater mussel,Cristaria plicata,under laboratory conditions.Clearance rate of Cu or Zn from water was highly dependent on exposure concentration.Interaction effect was most evident at 300μg·L^(-1) Cu exposure and depressed the Zn clearance rate significantly(p<0.05).However,the presence of 100μg·L^(-1) and 300μg·L^(-1) Zn hardly affected the Cu clearance rate.The 300μg·L^(-1) Cu presence enhanced Cu accumulation in each tissue most significantly(p<0.01),but caused Zn content to decrease in the gills by 62%(p<0.05),viscera by 49%(p<0.05)and foot by 31%(p<0.05),and increase in the mantle by 97%(p<0.05)and the muscles by 243%(p<0.05)for different Zn exposure treatments.The response of metal accumulation in various tissues of the test mussels indicated that Zn transferred from the gills,viscera and foot to the mantle and muscles might be one of the important characteristics of the Zn regulatory mechanism by leading to a narrow range of Zn concentration in the different tissues.
