A slow bromination process of butyl rubber(IIR) suffers from low efficiency and low selectivity(S) of target-product. To obtain suitable approach to intensify the process, effects of assistant solvents and mixing inten-sity on the bromination process were systemically studied in this paper. The reaction process was found constantly accelerated with the increasing dosage and polarity of assistant solvent. Hexane with 30%(by volume) dichloro-methane was found as the suitable solvent component, where the stable conversion of 1,4-isoprene transferring to target product(xA1s) of 80.2% and the corresponding S of 91.2% were obtained in 5 min. The accelerated reaction process was demonstrated being remarkably affected by mixing intensity until the optimal stirring rate of 1100 r·min?1 in a stirred tank reactor. With better mixing condition, a further intensification of the process was achieved in a ro-tating packed bed(RPB) reactor, where xA1s of 82.6% and S of 91.9% were obtained in 2 min. The usage of the suitable solvent component and RPB has potential application in the industrial bromination process intensification.
