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国家自然科学基金(s60878057)

作品数:2 被引量:3H指数:1
发文基金:国家自然科学基金国家高技术研究发展计划更多>>
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In-vivo retinal imaging by optical coherence tomography using an RSOD-based phase modulator被引量:1
2009年
Fourier-domain rapid scanning optical delay line (RSOD) was introduced for phase modulation and depth scanning in a time-domain optical coherence tomography (TD-OCT) system. Investigation of parameter optimization of RSOD was conducted. Experiments for RSOD characterization at different parameters of the groove pitch, focal length, galvomirror size, etc. were performed. By implementing the optimized RSOD in our established TD-OCT system with a broadband light source centered at 840 nm with 50 nm bandwidth, in vivo retina imaging of a rabbit was presented, demonstrating the feasibility of high-quality TD-OCT imaging using an RSOD-based phase modulator.
Ling WANGZhi-hua DINGGuo-hua SHIYu-dong ZHANG
All-fiber ring-cavity based frequency swept laser source for frequency domain OCT被引量:2
2010年
We develop a high-speed tunable, quasi-continuous-wave laser source for frequency domain (FD) optical coherence tomography (OCT). The laser resonance is realized within a unidirectional all-fiber ring cavity consisting of a fiber coupler, two fiber isolators, a semiconductor optical amplifier (SOA), and a fiber Fabry- Perot tunable filter (FFP-TF) for frequency tuning. Light output from the coupler is further amplified and spectral shaped by a booster SOA terminated at both ends with two isolators. The developed laser source provides up to 8000 sweeps per second over a full-width wavelength tuning range of 120 nm at center wavelength of 1320 nm with an average power of 9 mW, yielding an axial resolution of 13.6μm in air and a maximum sensitivity of about 112 dB for OCT imaging. The instantaneous linewidth is about 0.08 nm, enabling OCT imaging over an axial range of 3.4 mm in air. For optimization consideration based on this custom-built swept laser, experimental study on imaging quality relevant parameters of the swept laser with sine and ramp driving waveforms to the FFP-TF is conducted, and investigation of the swept laser on the cavity length is done. Implementing the laser source in our established swept source based OCT (SS-OCT) system, real-time structural imaging of biological tissue is demonstrated.
陈明惠丁志华徐磊吴彤王川史国华张雨东
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