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国家自然科学基金(61076023)

作品数:9 被引量:22H指数:2
相关作者:朱震奇王凯丰王会民王波钱亚龙更多>>
相关机构:北京大学更多>>
发文基金:国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划更多>>
相关领域:电子电信化学工程医药卫生机械工程更多>>

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Topping-off术后腰椎上位相邻节段退变的影像学分析被引量:4
2014年
[目的]研究不同方式腰椎后路短节段融合术后上位相邻节段退变(adjacent segment degeneration.ASD)的影像学变化特点。[方法]回顾分析本科2008年6月~2010年9月间所有行L4,后路椎间融合术(posterior lumbar interbody fusion,PLIF)+L3,4棘突间动态稳定手术(interspinous spacers,ISPs)病例共22例(Topping—off组,简称T组。Topping-off手术,即加顶技术,指PLIF联合近端节段ISPs手术),2007年1月-2008年5月间行L3-5,PLIF手术者共30例(Rigid Fixation组,简称R组)。采集患者围手术期数据,测量两组术前和末次随访时腰椎侧位X线片及过屈、过伸侧位x线片和MRI片,用统计软件SPSS19.0进行统计分析。[结果]两组患者性别、年龄、体重指数(Body Mass Index,BMI)、随访时间、围手术期情况差异均无统计学意义(P〉0.05)。侧位x线片两组L,,椎间隙前缘高度均略有增加、后缘高度和平均高度均略有降低、腰椎前凸角均增大,T组与R组间无显著统计学差异(P〉0.05);腰椎前凸角度T组自身比较差异有统计学意义(P〈0.05);L2,3椎间隙中立位角度和过伸位角度均增大、R组增大较T组有显著统计学差异(P〈0.05)。L2、3椎间隙过屈位角度和活动度(Range of Motion,ROM)均增大,R组与T组间比较差异无统计学意义(P〉0.05),过屈位角度R组内比较差异有统计学意义(P〈0.05)。x线片T组L2无影像学征象;R组有1例L2,3椎间盘高度下降〉20%,2例L2,3椎问ROM〉10°,诊断为影像学ASD。末次随访时,T组MRIT2相L2.3椎问盘改良Pfirrmann分级有2例升高1级,R组有8例升高1级、2例升高2级(包含x线片诊断ASD的3例),两组间差异有统计学意义(P〈0.05)。[结论]后路短节段Topping-off手术和PLIF手术的安全性和创伤性相似;术后2—5年内,Topping—off手术与PLIF手术相比,可能有助于延缓相邻节段�
许有银朱震奇刘海鹰钱亚龙王凯丰王会民王波
关键词:邻近节段退变椎间融合非融合
Low threshold voltage light-emitting diode in silicon-based standard CMOS technology被引量:2
2011年
Low-voltage silicon (Si)-based light-emitting diode (LED) is designed based on the former research of LED in Si-based standard complementary metal oxide semiconductor (CMOS) technology. The low-voltage LED is designed under the research of cross-finger structure LEDs and sophisticated structure enhanced LEDs for high efficiency and stable light source of monolithic chip integration. The device size of low-voltage LED is 45.85x38.4 (#m), threshold voltage is 2.2 V in common condition, and temperature is 27 ~C. The external quantum efficiency is about 10-6 at stable operating state of 5 V and 177 mA.
董赞王伟黄北举张旭关宁陈弘达
CMOS implementation of a low-power BPSK demodulator for wireless implantable neural command transmission
2012年
A new BPSK demodulator was presented.By using a clock multiplier with very simple circuit structure to replace the analog multiplier in the traditional BPSK demodulator,the circuit structure of the demodulator became simpler and hence its power consumption became lower.Simpler structure and lower power will make the designed demodulator more suitable for use in an internal single chip design for a wireless implantable neural recording system.The proposed BPSK demodulator was implemented by Global Foundries 0.35μm CMOS technology with a 3.3 V power supply.The designed chip area is only 0.07 mm;and the power consumption is 0.5 mW.The test results show that it can work correctly.
吴朝晖张旭梁志明李斌
A monolithic optical receiver chip for free space visible light communication system
This paper describes the monolithic optical receiver chip for next generation LED based free space optics(FSO)...
BeiJu HuangHongDa Chen
Motion-compensated interpolation for face-centered-orthorhombic sampled video sequence
2012年
Face-centered orthorhombic(FCO) sampling can be implemented more easily on CMOS image sensors than on other video acquisition devices.The sampling efficiency of FCO is the highest among all threedimensional(3D) sampling schemes.However,interpolation of FCO-sampled data is inevitable in bridging human perception and machine-vision algorithms.In this letter,the concept of motion compensation is borrowed from deinterlacing,which displays interlaced videos on progressively scanned devices.The combination of motion estimation based on intrafield interpolated frames and motion-compensated interfield interpolation is found to provide the best performance by evaluating different combinations of motion estimation and interpolation.
关宁张旭陈弘达
关键词:INTERPOLATION
Fabrication and characterization of implantable silicon neural probe with microfluidic channels被引量:1
2012年
In this paper, a silicon-based neural probe with microfluidic channels was developed and evaluated. The probe can deliver chemicals or drugs to the target neurons while simultaneously recording the electrical action of these neurons extracellularly. The probe was fabricated by double-sided deep reactive ion etching (DRIE) from a silicon-on-insulator (SO1) wafer. The flu- idic channels were formed with V-shape groove etching on the silicon probe and sealed with silicon nitride and parylene-C. The shank of the probe is 4 mm long and 120 ~tm wide. The thickness of the probe is 100 ~tm. The probe has two fluidic chan- nels and two recording sites. The microfluidic channels can withstand a pressure drop as much as 30 kPa and the flow resisti ity of the microfluidic channel is 0.13 μL min-1 kPa-1, The typical impedance of the neural electrode is 32.3 kΩ at 1 kHz at room temperature.
GUO Kai PEI WeiHua LI XiaoQian GUI Qiang TANG RongYu LIU Jian CHEN HongDa
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