The Xiaoxinancha Au-rich copper deposit is one of important Au-Cu deposits along the continental margin in Eastern China. The deposit consists of two sections: the Beishan mine (North), composed of altered rocks with veinlet-dissemination sulfides and melnicovite-dominated sulfide-quartz veins, and the Nanshan mine (South), composed of pyrrhotite-dominated sulfide-quartz veins and pure sulfide veins. The isotope compositions of noble gases extracted from fluid inclusions in ore minerals, i.e. ratios of 3He/4He, 20Ne/22Ne and40Ar/36Ar are in the ranges of 4.45―0.08 Ra, 10.2―8.8 and 306―430, respectively. Fluid inclusions in minerals from the Nanshan mine have higher 3He/4He and 20Ne/22Ne ratios whereas those from the Beishan mine have lower 3He/4He ratios. The analysis of origin, and evolution of the ore fluids and its relations with the ore-forming stages and the ages of mineralization suggests that the initial hydrothermal fluids probably come from the melts generated by partial melting of oceanic crust with the participation of fluids from the mantle (mantle-plume type)/aesthenosphere. This also corresponds to the continental margin settings during the subduction of Izanagi ocaneic plate towards the palaeo-Asian continent (123―102 Ma). The veinlet-dissemination ore bodies of the Beishan mine were formed through replacement and crystallization of the mixed fluids generated by mixing of the ascending high-temperature boiling fluid with young crustal fluid whereas the melnicovite-dominated sulfide-quartz veins were formed subsequently by filling of the high-temperature ore fluid in fissures. Pyrrhotite-dominated sulfide-quartz veins in the Nanshan mine were formed by filling-deposition-crystallization of the moderate-temperature ore fluids and the pure sulfide veins were formed later by filling-deposition-crystallization of ore substance-rich fluids after boiling of the moderate-temperature ore fluids. The metallogenic dynamic processes can be summarized as: (1) formation of fluidand ore substance-bearing