Objective:Cyclophilin A (Cyp A) is a ubiquitously distributed protein belonging to the immunophilin family and is recognized as the host cell receptor for the potent immunosuppressive
目的:观察脑缺血再灌注模型大鼠纹状体内多巴胺的动态变化,以及电针对该变化的影响。方法:运用微透析采样技术、高效液相检测技术,在多个时段对实验动物进行动态采样,观察缺血所致纹状体内多巴胺的变化,及电针风池穴对该变化的影响。结果:正常组、假手术组、假手术+电针组在观测时段内,细胞外多巴胺的变化没有显著差异,胞外多巴胺的含量在脑缺血后15-45 min 及再灌注后0-30 min 出现两个峰值(P<0.05)。再灌注后120 min 也观测到一次上升的趋势。经电针治疗后,胞外多巴胺的含量于再灌注后90 min 明显低于缺血组(P<0.05),再灌注后也未出现峰值。结论:电针风池穴能够调节多巴胺含量的紊乱,能够改善整体的神经功能。这可能是针灸治疗脑缺血再灌注损伤的机制之一。
目的:研究针刺治疗急性期中风的临床疗效。方法:150例中风急性期患者随机分为两组:药物组、针刺组,药物组采用神经内科常规药物治疗,脑复康250 mL,丹参注射液20 mL 加入生理盐水250 mL 中,静脉点滴,每日一次。针剌组除应用药物外,加"平肝潜阳法"针刺治疗。采用改良爱丁堡由斯堪的那维亚卒中量表(Scandinavian StrokeScale,SSS)、日常生活活动量表(ADL)(Barthel 指数)、血脂和血液流变学进行治疗前后对照观察。结果:量表结果显示针刺组与药物组相比有显著性差异,生化指标无特异性差异,血液流变学指标部分改善。结论:该量表能够较好的同步反映中风患者的临床症状及其变化,针刺疗法对急性期中风具有显著疗效。
Pulse diagnosis plays a vital role in Traditional Chinese Medicine(TCM).To extract effective and properfeatures from the wrist-pulse-signals is a crucial step for the recognition and classification of the pulsesignals.Although the analysis in the time domain is also very effective for a lot of pulse types(SHU et al.,2007),the frequency and time-frequency analysis are usually used in the literature(YAN et al.,2005;YUEet al.,2006)because the pulse signals are non-stationary and non-periodic time series in the pathologicalstates.In recent years,a new time-frequency analysis method,Hilbert-HUANG Transform proposed
