Insa and Pauer presented a basic theory of Grbner bases for differential operators with coefficients in a commutative ring and an improved version of this result was given by Ma et al.In this paper,we present an algorithmic approach for computing Grbner bases in difference-differential modules with coefficients in a commutative ring.We combine the generalized term order method of Zhou and Winkler with SPoly method of Insa and Pauer to deal with the problem.Our result is a generalization of theories of Insa and Pauer,Ma et al.,Zhou and Winkler and includes them as special cases.
