Graphene features a shining star in the material sciences since its discovery in 2004.Biomedical application of graphene-family materials has been driven recently.In this paper,we overviewed the cutting-edge research in the biomedical application of graphene-based biomaterials,such as bio-sensing and bio-imaging,drug/gene delivery and scaffold for tissue engineering.We emphasized on the effect of graphene substrates on cellular behaviors of adhesion,proliferation,and differentiation.The development of three-dimensional scaffolds based on graphenebased nanomaterials and the potential of these constructs in tissue engineering are discussed.The perspectives and challenges are also addressed.
Ning LiYilin ChengQin SongZiyun JiangMingliang TangGuosheng Cheng
