A series of zinc ions or/and cerium ions co-doped a-zirconium phosphate （Zn-Ce@ZrPs） were prepared. The novel Zn-Ce@ZrPs were characterized and the antibacterial activity on Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus were tested. The results showed that zinc ions （Zn2＋） or/and cerium ions （Ce3＋） were combined with ZrP, and the Ce3＋ was adsorbed on the surface of ZrP through hydrogen bonds, while Zn2＋ intercalated into the interlayer of ZrP. Zn-Ce@ZrPs showed excellent synergistic antibacterial activity. When Zn2＋/Ce3＋ atomic ratio was 0.6, the Zn-Ce@ZrP3 showed the highest synergistic antibacterial efficiency, suggesting great potential ap- plication as antibacterial agents in microbial control.
