Influence of plasma actuators as a flow separation control device was investigated experimentally. Hump model was used to demonstrate the effect of plasma actuators on external flow separation, while for internal flow separation a set of compressor cascade was adopted. In order to investigate the modification of the flow structure by the plasma actuator, the flow field was examined non-intrusively by particle image velocimetry measurements in the hump model experiment and by a hot film probe in the compressor cascade experiment. The results showed that the plasma actuator could be effective in controlling the flow separation both over the hump and in the compressor cascade when the incoming velocity was low. As the incoming velocity increased, the plasma actuator was less effective. It is urgent to enhance the intensity of the plasma actuator for its better application. Methods to increase the intensity of plasma actuator were also studied.