A simple and effective method for surface molecularly imprinted composite membranes(MICMs) for artemisinin(Ars) based on regenerated cellulose membranes was first prepared through surfaceinitiated atom transfer radical polymerization(ATRP),and the as-prepared MICMs were then evaluated as adsorbents for selective recognition and separation of Ars molecules.Batch rebinding studies were conducted to determine the specific adsorption equilibrium,kinetics and selective permeation performance.The adsorption capacity of MICMs toward Ars by the Langmuir isotherm model was2.008 mg g^(-1),which was nearly 5.0 times higher than non-molecularly imprinted composite membranes(NICMs).The kinetic property of MICMs was well-fitted by the pseudo-second-order rate equation.The selective permeation experiments were successfully investigated to prove the excellent selective permeation performance for Ars than the competitive analog(artemether).
In this study, novel molecularly imprinted open porous membranes(MIOPMs) were prepared using the Pickering HIPEs template method and molecular imprinting technology for selective adsorption and separation of methyl 4-hydroxybenzoate(M4HB). The template M4 HB, functional monomers,crosslinker and plastifier 2-ethylhexyl acrylate(2-EHA) were contained in the oil phase. Hydrophobic silica nanoparticles(HNP-Si O2) were employed as a stabilizer to establish stable W/O Pickering HIPEs with nonionic surfactant sorbitantrioleate(Span 85). The results of SEM and FTIR indicated that the optimal MIOPMs were prepared successfully and possessed open and interconnecting pores. Then, the MIOPMs were used as sorbents for M4 HB. The correlation coefficient(R2) values for the Langmuir–Freundlich isotherm model and pseudo-second-order kinetic model fitting to the adsorption equilibrium and kinetic data respectively were all higher than 0.95. The maximum adsorption capacity and the time of rapid adsorption for MIOPM4 were 4.146 mg g 1and 100 min, respectively. In addition, the permeability separation factor of MIOPMs for M4 HB compared to a structurally related analog methyl2-hydroxybenzoate(M2HB) could reach 3.122.
Hong-Yu LuoMin ZhangNai-Chao SiMin-Jia MengLi YanWen-Jing ZhuChun-Xiang Li
