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国家自然科学基金(81371292)

作品数:5 被引量:22H指数:3
相关作者:刘相名张东黄正邵军师唐凯更多>>
相关机构:首都医科大学附属北京天坛医院中南大学更多>>
发文基金:国家自然科学基金首都市民健康培育项目更多>>
相关领域:医药卫生更多>>

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Early postoperative infarction out of the middle cerebral artery distribution following superficial temporal artery-middle cerebral artery bypass: clinical features and pathogenesis被引量:5
2014年
The extracranial-intracranial (EC-IC) bypass surgery has been widely used in the treatment of cerebral ischemia,intracranial aneurysms,and other diseases for more than 40 years.In terms of treating atherosclerotic cerebral ischemia,the surgery is presumed to be helpful for the subgroup of hemodynamic compromise in prevention of subsequent stroke.However,two multicenter trials presented with high perioperative stroke rate and failed to demonstrate the profit of the surgery.1-3 On this point,one of the crucial issues currently is how to lower down the perioperative stroke rate,the centerpiece of which is early postoperative infarction (EPI).
Zhang DongHuang ZhenhuaZhao Jizong
小脑后下动脉动脉瘤的显微外科手术治疗被引量:3
2017年
目的 探讨小脑后下动脉(PICA)不同部位动脉瘤采用不同手术入路的临床效果.方法 回顾性纳入首都医科大学附属北京天坛医院神经外科2011年9月至2016年8月对29例PICA动脉瘤进行开颅手术治疗的患者,根据动脉瘤的不同部位分别采用枕下后正中入路(12例)、枕下远外侧入路(7例)和枕下乙状窦后入路(10例)夹闭或切除动脉瘤.术后对其临床表现、手术方式、治疗效果进行分析总结.结果 29例PICA动脉瘤中,完全夹闭25例,部分夹闭并加固1例,完整切除1例,术中仅切除畸形未切除动脉瘤1例,切除动脉瘤后行端-端吻合1例.其中2例术后出现皮下积液行二次清创缝合,1例死亡,1例植物生存,11例出现吞咽困难、声音嘶哑等后组脑神经症状,17例无术后新发神经功能障碍.术后22例(76%)行影像学复查未见动脉瘤残留,6~ 63个月随访患者后组脑神经症状均有不同程度地改善.格拉斯哥预后分级(GOS)Ⅴ级26例,Ⅳ级1例,Ⅲ级0例,Ⅱ级1例,Ⅰ级1例.结论 PICA不同部位的动脉瘤采用不同的手术入路可取得良好的临床效果,术前评估PICA的走形特点及动脉瘤的病理特征对手术方式的选择非常重要.虽然术后近期并发症较高,但术后长期随访结果比较满意.
尹乾坤刘相名朴明学唐凯张岩张东
关键词:颅内动脉瘤小脑后下动脉显微外科手术
Quality improvement of nursing on patients with complex cerebral arteriovenous malformation undergoing hybrid surgery:a prospective single-center study被引量:5
2021年
Background:We sought to explore an optimal clinical nursing mode following a hybrid surgery for cerebral arteriovenous malformation.Methods:Patients with complex cerebral arteriovenous malformations seen in our neurosurgery department from January 2016 to December 2017 were prospectively enrolled.The hybrid surgery protocol included“angiographic diagnosis,surgical resection,and intraoperative angiographic evaluation”and“angiographic diagnosis and embolization,surgical resection,and intraoperative angiographic evaluation”.The patients were randomly stratified into intensive care group and routine care group.After surgery,intensive or routine care was provided,and the prognosis of patients was evaluated,with a subsequent comparative analysis.Results:A total of 109 cases were divided into the routine nursing group(n=54 cases)and intensive nursing group(n=55 cases).There were no significant differences between the two groups in baseline data before surgery.Postoperative lung infection in the intensive nursing group was significantly less frequent than those in the routine nursing group(5.5%vs.18.5%,P=0.039)with pulmonary infection and lower extremity venous thrombosis(5.5%vs.24.1%,P=0.006).The average hospital stay in the intensive nursing group was 14.4±5.78 days,which was significantly lower than that in the routine nursing group(19.3±6.38 days,P=0.013).At 3 months’follow-up after surgery,the Generic Quality of Life Inventory-74(GQOLI-74)dimension score and GQOLI-74 total score in the enhanced group were significantly better than those in the routine nursing group(P=0.017 and 0.023,respectively).Conclusions:Intensive postoperative nursing can improve the safety of patients after hybrid surgery,reduce the postoperative complications and the average length of hospital stay,and improve the quality of life of patients.
Dong-Hong ZhaoRui XueXiao-Rong Sun
经Dolenc入路治疗颅内复杂部位动脉瘤17例临床分析被引量:3
2017年
目的探讨采用Dolenc入路开颅手术治疗颅内复杂部位动脉瘤的临床效果。方法回顾性分析2014年11月-2016年1月,首都医科大学附属北京天坛医院神经外科经Dolenc入路开颅手术夹闭治疗的17例颅内复杂部位动脉瘤患者的临床资料,其中男7例、女10例,年龄41-72岁,包括颈内动脉床突段动脉瘤4例、眼动脉段动脉瘤8例、基底动脉顶端动脉瘤1例、大脑后动脉动脉瘤2例、前循环合并后循环多发动脉瘤2例(均一次手术夹闭)。结果17例患者完全夹闭动脉瘤;除2例患者术后出现同侧动眼神经麻痹,其中1例患者出现同侧额叶梗死灶外,其他患者术后均未出现并发症。所有患者术后6个月门诊复诊,均未见动脉瘤复发,未见手术后遗症,格拉斯哥预后评分平均为4.8分。结论对于颅内一些特殊部位动脉瘤的开颅手术夹闭治疗,相对于传统的入路方式,Dolenc入路具有明显的优势,手术的安全性高。
刘相名喻乐保黄正邵军师张东
关键词:颅内动脉瘤手术入路前床突
Carotid endarterectomy for treatment of carotid in-stent restenosis:longterm follow-up results and surgery experiences from one single centre被引量:6
2017年
Objective Few studies have reported the surgical treatment of carotid in-stent restenosis(ISR),more data and longer follow-up are needed.We describe the surgical treatment of ISR by standard carotid endarterectomy(CEA)with stent removal,including long-term follow-up in 10 patients from our centre.Methods Ten patients from our centre who underwent CEA with stent removal for ISR were retrospectively analysed,including nine symptomatic and one asymptomatic ISR of at least 70%with mean age 67.3,the median time between carotid artery stenting and CEA was 17 months(range,2-54 months).results Standard CEA with stent removal was performed in all 10 patients without much technical difficulty(9 male and 1 female,mean age 67.3).Two cases were performed in hybrid operation room.There were a total of three complications that happened in three patients(30%)respectively.An asymptomatic dissecting aneurysm was formed on the petrous internal carotid artery in one patient who was followed up without intervention.In the second case,dissection occurred in the arterial wall distal to the site of the stent after stent removal revealed by intraoperative angiography,and another stent was implanted.The patient sustained temporary hypoglossal nerve dysfunction postoperatively.The third patient suffered cerebral hyperperfusion with complete recovery when discharged.No neurological complications occurred in other seven patients.After follow-up of 25 months(range,11-54 months),one patient died of rectal cancer without ischaemic attack and restenosis 4 years postoperation;in one patient occurred recurrent symptomatic restenosis(90%)1 year later;all other patients remained asymptomatic and without recurrent restenosis(>50%)by follow-up carotid ultrasound or CT angiography.conclusion It seems that CEA with stent removal is a reasonable choice,by experienced hand,for symptomatic ISR with higher but acceptable complications.The indication of stent removal for asymptomatic ISR needs further observation.
Le-Bao YuWei YanQian ZhangJi-Zong ZhaoYan ZhangRong WangJun-Shi ShaoDong Zhang
关键词:CAROTIDRESTENOSISSUSTAINED
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