Acute Yin impairment is a frequently occurring clinic syndrome. We suggest the process of acute Yin impairment be divided into two stages, namely early impairment of lung and stomach fluid and later Yin impairment of liver and kidney. This work aims to research into the cell protecting mechanism of Zengyetang, from the angle of protecting cells, change of inner and outer fluid ion of cells, change of enzyme of cell membrane, free radical impairment, appoptosis and gene expression. The study, taking inner and outer fluid ion of cells as objective indicators, also researches into dynamic change of inner and outer fluid of cells in the different stages of Yin impairment development on the animal models of yin impairment by fever and poison. Zengyetang is one of the typical Yin nourishing prescriptions. Zengyetang is made into injection in accordance with the rate of the original prescription. This work researches into the affects of Zengyetang on the four types of acute Yin impairment animal models, including Yin impairment model by pathogenic heat, Yin impairment model by summer heat and sweat, Yin impairment model by high infiltration Yin impairment and Yin impairment by drugs and toxin. Main experiment results show:1. in early stage, pathogenic heat Yin impairment impairs outer liquid of cells; 2. Zengyetang has the function of adjusting disorder of inner and outer fluid of red cells; 3. Zengyetang has the function of protecting enzyme activity of cell membrane and maintaining normal operation of red cell ion; 4. Zengyetang can protect liver cells of rabbits through resisting free radical impairment and lessen thymocyte apoptosis of young rat resulted from glucocorticoid.
住院医师规范培训(住培)是医学生毕业后教育的重要组成部分[1]。在临床培训过程中,有多种针对专业知识和技能的评价工具可供选择,尚缺乏有关医学人文素养的评价体系[2]。2011年,美国毕业后医学教育认证委员会(Accreditation Council for Graduate Medical Education,ACGME)开发和实施了住院医师教育"里程碑"评价体系,用于持续评价住院医师各项能力和人文素养[3,4]。
