Drought, one of the major natural disasters, has attacked Yunnan frequently in recent years, seriously undermining the sustainable development of society and economy and ecological civilization construction. As to the series of drought, this study has expounded the necessity and urgency of human-land relationship regulation in drought control and disaster release, from the aspect of human factorsthe inharmonious relationship between human and land. Based on that, the main countermeasures of drought control and disaster release have been further explored, in order to provide references for the future drought control and disaster release in Yunnan.