Screenings for phenyl keton nria (PKU)and congenital hypothyroidism (CH) are effective measures to prevent low intelligence of children due to congenital metabolic diseases. Shanghai started screening project for the neonaes in 1981, and 1 050 914neonates has been screened up to now with 95% coverage.Incidence of PKU is 1/17 237, and that of CH is 1/5 082. Children with positive tests received qualified treatment with remarkable effectiveness.It plays a positive role to improve the quality of population in Shanghai.This study undetakes cost benefit analysis of screening for the neonates in the view of health economics , which provides basis of decision for haalth executitre department.
