Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids(compounds Ⅱ o,Ⅱ m,Ⅱ p) have been synthesized using a phase transfer catalyst(CTAB) in dichloroethane/water at 50 ℃. Their structures have been confirmed by elemental analysis, IR, 1H NMR and MS. The compounds were found to have antianemic activity. The RBC and HB values of the tested anemic rats were increased by 72 0% and 126 4%, respectively after abdomen injection.
Eight glucoside compounds were synthesized in 41.0-65.9% yields by reaction of 2,3,4,6-era-O-acetyl-α-D-glucopyranosyl bromide with corresponding phenols,using cetyltrimethyl ammonium bromide as a phase-transfer catalyst.In their IR spectra the absorption of bending vibration of C1-H bond in glycosyl-ring appears at about 900cm-1.In their 1H NMR spectra anomeric C1-H appears as a doublet as 5.08-5.14ppm with a coupling constant J1-2=7.8-8.0Hz.All these prove that these glucoside compounds have the configuration of β-anomer.The method has advantages of mild reaction conditions,easy separation and high stereospectificity of the products.
