Diorganotin(Ⅳ) compound [(p-CNC6H4CH2)2Sn(C9H7N3O3)(H2O)]2 was synthesized by the reaction of tri-p-cyanobenzyltin chloride with Schiff base ligand pyruvic acid isonicotinyl hydrazone. The compound was characterized by elemental analysis, IR, 1H NMR. The crystal structure was determined by X-ray single crystal diffraction. The crystal belongs to monoclinic space group C2/c, with a=3.143 1(3) nm, b=0.989 99(10) nm, c=1.785 68(18) nm, β=114.908 0(13)°, V=5.039 6(9) nm3, Z=4, μ=1.054 mm-1, Dc=1.513 Mg·m-3, F(000)=2 304, R=0.042 8, wR=0.090 3, GOF=0.997. In this compound, the Sn atom exists in a distorted octahedral coordination environment in which one water molecule, one tridentate pyruvic acid isonicotinyl hydrazone ligand, and two trans p-cyanobenzyl groups coordinate to each Sn center, the angle of the axial C10-Sn1-C18 is 166.1(2)°. Two molecules form a weak-bridged dimmer with weak interactions of Sn...O bonding and hydrogen bonds. CCDC: 270796.
The title complex {[%n%|Bu-2SnO-2CCH(CS-2NEt-2)-2]-2O}-2 was synthesized and characterized by elemental analysis, IR, NMR and X|ray single crystal diffraction. The results show that the complex belongs to a monoclinic system with space group %C2/c%, and unit cell dimensions: %a%=2.848(5) nm, {%b%=1.381(2) nm}, %c%=3.239(6) nm, %β%=111.11(2)°, %Z=4, V%=11.884(35) nm+3, %D%-c=1.329 g/cm+3, {%F%(000)}=4 912, %S=0.991, R-1=0.053 5, wR-2=0.116 6.% The complex has a centrosymmetric dimer structure mode with a four|membered central %endo%|cyclic Sn-2O-2 unit. The %endo%|cyclic tin atoms are six|coordination and have coordition geometry of distorted octahedron. The %exo%|cyclic tin atoms are five|coordination and have coordination geometry of distorted trigonal bipyramid. This complex was tested %in vitro% against human tumour cell lines, MCF-7 and WiDr, and displayed the higher activity.
The tri(o-chlorobenzyl)tin ester of 2-indolylcarboxylic acid has been synt hesized and characterized by elemental analysis, IR and 1H NMR. The crystal stru cture has been determined by X-ray single crystal diffraction. The crystal belon gs to triclinic with space group P1, a=1.020 0(16) nm, b=1.125 9(18) nm, c=1.321 (2) nm, 8)穖-3,
