The research of the cooperative antivirus activities was carried out using amantadine, ribavirin and herby houttuynia. The inhibitory effect of CPE caused by influenza virus A\-3 in MDCK cell and the therapeutic effect on BALB/c mice pneumonia caused by influenza virus FM1 were examined and analyzed when amantadine, ribavirin and herby houttuynia were used alone or associatively. The results show that the concentrations of amantadine,ribavirin and herby houttuynia with same effect were 256, 512 and 1024 times cooperatively as many as alone in vitro, respectively.The ablities of treating pneumonia of mice when three kinds of drugs were used cooperatively were far higher than those alone in BALB/c mice.
