以天然植物杨木作为大孔硬模板,以嵌段共聚物P123作为介孔相软模板成功制备出一种具有连续的骨架和相互贯通的大孔孔道,其大孔孔径约为10μm,其孔壁为介孔相的高度有序多级复合孔材料。并用扫描电子显微镜(SEM)、粉末X射线衍射仪(X R D)、高分辨率透射电镜(H R TEM)、N2吸附-脱附等测试手段对样品进行了系统的表征。结果表明,合成的产物是孔道相互贯通的多级有序复合孔硅材料。该复合孔材料在生物大分子分离、骨组织修复以及药物缓释等方面将具有广泛的应用前景。
A series of mesoporous silica with variable pore structures were prepared.The influence of mesoporous structure on drug release profiles was studied.It is found that mesoporous pore structure has a great effect on the drug release rate.The cubic pore structure MCM-48 has a faster drug release rate than that of MCM-41 system;while SBA-16 with 'cage-like' pore structure system has the lowest drug release rate.
