[ Objective] The paper was to screen Bacillus with strong antagonistic effect. [ Method] The diseased ginger and the surrounding soils were collected from Laiwu of Shandong Province, and the high-virulence strains of the pathogen of ginger blast (Ralstonia solanacearum) were isolated, Bacillus was used to carry out antagonistic test. [Result] Three strains LW-4, LW-7 and LW-32 had strong antagonistic effect against R. solanacearum, the area of their inhibition zone was larger than other strains. [ Conclusion] The study provided theoretical basis for the control of ginger blast.